Reddish-yellow blotches on mature leaves of variegated holly typically indicate fungal leaf spot, often caused by Cercospora species. New leaves naturally emerge reddish, but established leaves changing color signal disease.
Existing spots won't disappear, but new growth should emerge clean. Continue preventive sprays in spring as leaves unfurl.
If these fungicides aren't available in your region, contact your local extension for approved alternatives.
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