Random yellow leaves with brown/tan spots and purple-black borders on mature holly in West Virginia indicate Cylindrocladium leaf spot. Common on 'Burford', Japanese, American, and yaupon hollies. Single spots cause premature leaf drop; severe cases lead to shoot dieback.
Apply fungicide (e.g., Ortho Multi-Purpose Fungicide/Daconil 2787) at leaf-out, repeat every 10–14 days until shoot growth stops. Only treat previously damaged plants. Check local nursery for other labeled products.
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