18–20 yr fruitless mulberry in Cottonwood, AZ shows brown spots, leaf drop. Home Depot recommended Bayer 3-in-1 (contains neem). Owner asks fall vs. spring timing.
Spraying dying leaves is useless—no tissue left to protect. The spots are likely Cercospora or similar leaf spot fungus, favored by a wet year.
Mulberries are short-lived; at 20 yrs, decline is normal. If problems persist yearly, plan replacement.
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