A western Kentucky gardener's weeping mulberry shows white powdery substance on branches since late summer. Fruit tree spray (insecticide + fungicide combo) failed. The diagnosis: powdery mildew.
Combo products contain low fungicide rates optimized for fruit diseases (scab, brown rot), not powdery mildew. Mildew requires specific fungicides at higher rates.
Powdery mildew rarely kills established trees but weakens them and ruins appearance. Consistent treatment restores vigor. See OSU fact sheet: ohioline.osu.edu/hyg-fact/3000/3047.html
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