No. Plants respire mainly through stomata on leaf undersides, where dust doesn't settle. However, dust on upper surfaces blocks light, reducing photosynthesis. Clean when dust is visibly noticeable.
It's mineral residue (calcium, salts) from guttation—water droplets exuded from leaf margins when roots absorb more water than leaves can transpire. Harmless; wipe off or leave.
No. Unnecessary repotting is the #1 cause of houseplant death. Dieffenbachias prefer being potbound. Repot only if soil dries out in <2 days after thorough watering. Your current regimen (water every 2 weeks, occasional fertilizer, top-dressing) is fine.
Your long-lived plants are thriving—don't fix what isn't broken!
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