Question

Disease branch   Branches form holes large knots branch dies tree lumpy

Answer
Hi Jeff,

By my observations in the photo, it appears that you have some gall formation.  These are usually the result of fungal infestations or, in some species, bacterial infections (e.g._Agrobacterium tumifaciens_.

I would suggest consulting an tree specialist or your extension service in your area.

Good luck, and good gardening.