Your pothos (Epipremnum aureum) shows vigorous new growth at the base and vine tips, but the middle leaves develop brown or yellow spots. The clue is in the spacing: leaves are farther apart than the ideal 1 inch per node. This indicates insufficient light.
In low light, pothos produces thin, soft leaves with less waxy cuticle and reduced cellular defenses. These leaves are prime targets for fungal pathogens (commonly Phyllosticta, Colletotrichum, or Cercospora species) that cause leaf spot. The spots typically appear on older, interior leaves first because they're the most shaded and physiologically oldest.
With better light and prompt leaf removal, new growth will be tighter, stronger, and resistant to spotting.




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