Modern pressure-treated lumber uses alkaline copper quaternary (ACQ) or micronized copper azole (MCA), which are far less toxic than the old chromated copper arsenate (CCA). Research indicates minimal leaching into soil, and the copper actually binds to organic matter.
Most experts, including university horticulturists, consider modern treated wood safe for raised beds without a liner. If you remain concerned, line the interior with heavy-duty landscape fabric, but it is generally unnecessary.
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